[MCOH-EH] [Bulk] Re: Quantiferon gold TB test - preplacement question

Kathy Dayvault KDayvault11 at att.net
Wed Jul 30 11:15:25 PDT 2014

A TB skin test and QuantiFERON gold tests are different testing
methodologies.. hard to compare your results.


Blood tests for TB have a higher sensitivity and specificity when it comes
to detecting latent TB.



Kathy Dayvault, RN, BSN, MPH, COHN-S/CM

Independant Occupational Health Nurse Consultant

JET Consulting

kdayvault11 at att.net






From: MCOH-EH [mailto:mcoh-eh-bounces+kdayvault11=att.net at mylist.net] On
Behalf Of Morelli, Karen J
Sent: Wednesday, July 30, 2014 2:07 PM
Subject: [Bulk] Re: [MCOH-EH] Quantiferon gold TB test - preplacement


I assume you meant to type that the Quantiferon is positive now after a
negative ppd one month ago.  I have been monitoring the Quantiferon issue
since we had a cluster of false positives last fall (presumably due to
tube/process issues).  The research I have done states that Quantiferon
could be run within a 3 day window of receiving a ppd, after that there is a
chance of getting a false positive reading on the Quantiferon (from the ppd
plant).  There is no concrete "cut off" time frame that I have seen to know
when it would be okay to run a Quantiferon after a ppd.  The TB expert in my
area stated that false positive Quantiferon tests have been noted up to 6
weeks after a ppd.  Due to the uncertainty of when it would be okay to run a
Quantiferon after a ppd, our department has adopted a 6 months cut off time.


Thank you,

Karen Morelli RN, BSN

Eastern Maine Healthcare Systems


From: MCOH-EH [mailto:mcoh-eh-bounces at mylist.net] On Behalf Of Band, Michael
Sent: Wednesday, July 30, 2014 1:41 PM
To: mcoh-eh at mylist.net
Subject: [MCOH-EH] Quantiferon gold TB test - preplacement question


Currently we are using the quantiferon gold TB test for use after a positive
ppd for preplacement.


Every once in a while a new doctor or employee are not available for a 48-72
hour ppd read so we do quantiferon instead.


Had a new doctor with a negative ppd one month ago at another facility and
her quantiferon gold is negative.


NO symptoms of active TB and no known exposures.  She is in a low risk
specialty for TB exposure.


Chest xay normal




1.       I read somewhere that a recent ppd can interfere with the
quantiferon gold test.  Not sure if this is true?


2.      What is the next step?  Do we call this latent Tb?  Is it worth
repeating the quantiferon gold test?  Could this be a false positive?


Thanks for any help.


Michael Band DO, MS

Watson Clinic


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