[MCOH-EH] TB testing and COVID-19 vaccine: update from CDC

[Rolando, Lori]

Hi all,

Just in case folks hadn't seen this, wanted to let the list serve know that the CDC has officially updated their guidance on TB testing in the context of recent COVID-19 vaccination.

We no longer need to consider when someone has had a COVID-19 vaccine when administering a TB test as noted below:



"Use of immune-based tests for tuberculosis infection, such as the tuberculin skin test and interferon-gamma release assay

COVID-19 vaccination should not be delayed because of testing for tuberculosis (TB) infection. Testing for TB infection with one of the immune-based methods, either the tuberculin skin test (TST) or an interferon release assay (IGRA)<https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.cdc.gov%2Ftb%2Ftopic%2Ftesting%2Ftbtesttypes.htm&data=04%7C01%7Clori.rolando%40vumc.org%7C69b09ec55c744f7f2b5608d96d8182f2%7Cef57503014244ed8b83c12c533d879ab%7C0%7C0%7C637661225695905769%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=6KUjJUEKVUaHHDtJhQXwywRgOEGKo24WNSt8Yovec1M%3D&reserved=0>, can be done before, after, or during the same encounter as COVID-19 vaccination

TSTs and IGRAs were previously recommended to be administered > 4 weeks after completion of COVID-19 vaccination to minimize potential theoretical interference between vaccination and TB testing. This was out of an abundance of caution during a period when these vaccines were new. However, given logistical challenges faced in delaying TB infection testing, the recommendation has been updated so that these tests may now be administered without regard to timing of COVID-19 vaccination.

source:

Interim Clinical Considerations for Use of COVID-19 Vaccines | CDC<https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.cdc.gov%2Fvaccines%2Fcovid-19%2Fclinical-considerations%2Fcovid-19-vaccines-us.html&data=04%7C01%7Clori.rolando%40vumc.org%7C69b09ec55c744f7f2b5608d96d8182f2%7Cef57503014244ed8b83c12c533d879ab%7C0%7C0%7C637661225695905769%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=td%2FBMEXp9WPGoS7U6YYKYeiROFs3SS5bNGhf95Liy0s%3D&reserved=0>

Thanks so much,
Lori

Lori Rolando MD MPH FACOEM
Director, Vanderbilt Occupational Health Clinic
615-936-0955 (p)
615-936-0966 (f)

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