[MCOH-EH] Question re: JYNNEOS vaccine and breastfeeding

[Gochnour, Michelle K.]

Wondering how any of you are approaching questions regarding breastfeeding and the JYNNEOS vaccine.  We had a situation come up where the child who is breastfeeding has eosinophilic esophagitis (EOE) and a severe allergy to eggs;  and should one be concerned about chicken protein exposure impact on EGG allergy through breast milk?

Also, the JYNNEOS package insert and June 3 MMWR states data are not available to assess the safety of JYNNEOS in breastfed infants, but goes on to state that because the vaccine is replication-deficient, it likely does not present a risk of transmission to breastfed infants and can be administered to women who are breastfeeding if vaccination is critical.   (Note: the person in question is a researcher planning to work with MPXV positive patient samples and our policy is to require vaccination for research work).  Further, myocarditis has mainly been seen in young adult/adolescent men post COVID-19 vaccination and there is an unknown risk of myocarditis post JYNNEOS vaccine.  Given this logic, would you agree that the risk for myocarditis to INFANT males who have received mRNA COVID-19 vaccine and are breastfeeding with a mother who receives JYNNEOS vaccine is low to none?

Thanks for any/all thoughts!

Michelle Kom Gochnour
Senior Occupational Health & Safety Consultant, Research | Environmental Health and Safety
Seattle Children's

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