Yes, had this happen more than once with T-Spot. Per their website:
Borderline results are clinically interpretable and should be followed. Retesting by collecting another sample is recommended. In a study of U.S. healthcare workers, 23% of subjects with a borderline test result retested as positive, suggesting the borderline category is useful in maintaining test sensitivity. Upon retesting, if the test result remains borderline, other diagnostic tests and/or epidemiologic information should be used to help determine the TB infection status of the patient.1
1. King TC, Upfal M, Gottlieb A, et al. T-SPOT.TB Interferon-ã Release Assay Performance in Healthcare Worker Screening at Nineteen U.S. Hospitals. Am J Respir Crit Care Med. 2015;192(3):367-373. doi:10.1164/rccm.201501-0199OC.
Christy Rossiter, RN, CMSRN
Employee Health Coordinator
700 Lawn Ave
Sellersville, PA 18960
We use Interferon Gamma Release Assays ( IGRA) to test for tuberculosis on all new employees. I have one new employee that I have tested twice (with approx one month in between testing) and both times the results were borderline. Has anyone else had this come up and if so what did you do next? This employee has no symptoms and no high risk activity such as traveling outside the country or having contact with anyone with known Tb.
Cathy Senior RN BSN CDE
Employee Health Director
Penn Highlands DuBois
100 Hospital Avenue
P.O. Box 447
DuBois Pa 15801
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