Hello all
I was part of the study that was quoted——borderline is not negative and not positive and should be repeated in 8-10 weeks. 25% of borderlines go on to be positive. At our facility we do not make a pre-placement candidate wait 8-10 weeks, we obtain a CXR.
Incumbents-as long as they are symptom free, we wait that amount of time. The CDC does not want us to go from one test method to another(IGRA to skin test). 

My experience with this testing has been really good.

Phil Adamo
Baystate Health
On Apr 25, 2016, at 12:29 PM, Employee Health <employeehealth@gvh.org> wrote:

Yes,  had this happen more than once with T-Spot.   Per their website:
What should I do with a borderline T-SPOT.TB test result?
Borderline results are clinically interpretable and should be followed. Retesting by collecting another sample is recommended. In a study of U.S. healthcare workers, 23% of subjects with a borderline test result retested as positive, suggesting the borderline category is useful in maintaining test sensitivity. Upon retesting, if the test result remains borderline, other diagnostic tests and/or epidemiologic information should be used to help determine the TB infection status of the patient.1
1. King TC, Upfal M, Gottlieb A, et al. T-SPOT.TB Interferon-γ Release Assay Performance in Healthcare Worker Screening at Nineteen U.S. Hospitals. Am J Respir Crit Care Med. 2015;192(3):367-373. doi:10.1164/rccm.201501-0199OC.
Christy Rossiter, RN, CMSRN
Employee Health Coordinator
700 Lawn Ave
Sellersville, PA 18960
Telephone: 215-453-4016
Fax: 215-453-4748
From: MCOH-EH [mailto:mcoh-eh-bounces@mylist.net] On Behalf Of Senior, Cathy (Employee Health)
Sent: Monday, April 25, 2016 12:12 PM
Subject: [MCOH-EH] IGRA
We use Interferon Gamma Release Assays ( IGRA) to test for tuberculosis on all new employees.  I have one new employee that I have tested twice (with approx one month in between testing) and both times the results were borderline.  Has anyone else had this come up and if so what did you do next?  This employee has no symptoms and no high risk activity such as traveling outside the country or having contact with anyone with known Tb. 
Cathy Senior RN BSN CDE
Employee Health Director
Penn Highlands DuBois
100 Hospital Avenue
P.O. Box 447
DuBois Pa 15801
Phone 814-375-3392
Fax 814-372-2610
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