Hi Tim,
Per the MMWR / January 12, 2018 / Vol. 67 / No. 1 US Department of Health and Human Services/Centers for Disease Control and Prevention.
https://www.cdc.gov/mmwr/volumes/67/rr/pdfs/rr6701-H.PDF
“Response to Revaccination”
A challenge dose of HepB vaccine may be used to determine the presence of vaccine-induced immunologic memory through generation of an anamnestic response. The
term “booster dose” has been used to refer to a dose of HepB vaccine administered after a primary vaccination series to provide” (page 12, bottom right).
We utilize this method and have found that the majority will convert to immunity status.
However, we use the Engerix Hep B (01 ml). After booster vaccination, we schedule a Titer retest 6 – 8 weeks later
Thank you,
Kim A. Norton, B.S.N., R.N., O.H.N.
Occupational Health Services & Injury Coordinator
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From: MCOH-EH <mcoh-eh-bounces@mylist.net>
On Behalf Of Tim Crump
Sent: Tuesday, August 20, 2019 3:08 PM
To: MCOH-EH <mcoh-eh@mylist.net>
Subject: {EXTERNAL} [MCOH-EH] Can Heplisav-B be used for booster dose?
We are transitioning over to mostly Heplisav-B for our Hep B vaccinations. Does anyone have thoughts whether Heplisav-B can be used for a booster dose? (For example, if a worker had a full documented Hep B series
in 2001, but never got a titer till now and it is negative, can we use one Heplisav-B for booster dose, and if the worker has a positive titer after, call them long-term immune?)
·
Our drug rep says no, that Heplisav is always given as a series of 2 and never as a single dose.
·
To my mind though, anyone with a full Hep B series and a subsequent positive titer has long term immunity, and it shouldn’t matter which vaccine boosts to demonstrate this.
What do others think? The advantage of boosting w/ Heplisav-B would be that if the titer is negative, it would take a lot less time to complete the second series. Best, Tim
Tim Crump, MSN, FNP
Tim Crump, MSN, FNP
Family Nurse Practitioner
Multnomah Pavilion 1 SE, Suite 1110
Occupational Health
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